GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2294008 | 1 | rs2920294 | chr8:143765326 | PSCA | chr8:143761875-143764142:+ | 0.43 | 4.3 | 4.13E-5 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| THYM | cis | rs2294008 | 1 | rs2920295 | chr8:143764937 | PSCA | chr8:143761875-143764142:+ | 0.43 | 4.3 | 4.13E-5 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| THYM | cis | rs2294008 | 1 | rs2920296 | chr8:143763109 | PSCA | chr8:143761875-143764142:+ | 0.43 | 4.29 | 4.22E-5 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| THYM | cis | rs2294008 | 1 | rs2920297 | chr8:143763083 | PSCA | chr8:143761875-143764142:+ | 0.43 | 4.29 | 4.22E-5 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| THYM | cis | rs2294008 | 1 | rs2920298 | chr8:143763043 | PSCA | chr8:143761875-143764142:+ | 0.43 | 4.29 | 4.22E-5 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| THYM | cis | rs2251844 | 1 | rs2920781 | chr15:43924682 | ADAL | chr15:43622872-43646094:+ | -0.51 | -4.38 | 3.06E-5 | Tumor biomarkers |
| THYM | cis | rs2251844 | 1 | rs2927072 | chr15:43922398 | ADAL | chr15:43622872-43646094:+ | -0.51 | -4.38 | 3.06E-5 | Tumor biomarkers |
| THYM | cis | rs9314614 | 1 | rs2951851 | chr8:6693495 | XKR5 | chr8:6666043-6693037:- | -0.45 | -5.03 | 2.27E-6 | IgA nephropathy |
| THYM | cis | rs2243480 | 1 | rs2961102 | chr7:65424658 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 5.29 | 7.77E-7 | Diabetic kidney disease |
| THYM | cis | rs2294008 | 1 | rs2976392 | chr8:143762932 | PSCA | chr8:143761875-143764142:+ | 0.43 | 4.29 | 4.22E-5 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| THYM | cis | rs2294008 | 1 | rs2976394 | chr8:143763622 | PSCA | chr8:143761875-143764142:+ | 0.43 | 4.29 | 4.22E-5 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| THYM | cis | rs2294008 | 1 | rs2976396 | chr8:143764001 | PSCA | chr8:143761875-143764142:+ | -0.43 | -4.29 | 4.22E-5 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| THYM | cis | rs2294008 | 1 | rs2976398 | chr8:143764879 | PSCA | chr8:143761875-143764142:+ | 0.43 | 4.3 | 4.13E-5 | Gastric adenocarcinoma (histologically verified);Non-cardia gastric cancer;Gastric cancer;Duodenal ulcer;Bladder cancer |
| THYM | cis | rs2977993 | 1 | rs2977993 | chr9:131608786 | ENDOG | chr9:131580779-131584954:+ | 0.22 | 4.41 | 2.76E-5 | Schizophrenia |
| THYM | cis | rs9314614 | 1 | rs2978894 | chr8:6693629 | XKR5 | chr8:6666043-6693037:- | -0.42 | -4.52 | 1.76E-5 | IgA nephropathy |